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Aging Intervention Medicine

Treating Aging as a Disease

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Most us believe that reversing biological age is impossible and remain completely oblivious to the fact that biological age reversal is an accepted fact in the scientific community. Whether or not this younger biological age translates into a longer life remains a question that can only be answered in time. Logic would seem to indicate if our biological age is the same as someone a decade chronologically younger, that we will live a bit longer.

HOW IS AGING DEFINED

We all suffer from this ailment we call 'aging'. Generally, when used in connection to health related issues, 'aging' usually refers to the slow decline of physical and mental health that occurs over the passing of chronological years. Because this slow decline in health seems to occur as sure as the clock ticks, we treat this decline in health as if it's inevitably locked in step with the time. That is not the case.

While associating the early aging /growth process from adolescence to adult maturity has useful application in modern society, there is strong evidence that the rate at which an individual 'ages' occurs without regard to the number of chronological years that pass. Breakthroughs in medicine and cutting-edge science has shown in human clinical trials biological age can be slowed, stopped, or even reversed.

AGE REVERSAL & TREATING THYMIC INVOLUTION

In several FDA approved clinical trials known as the TRIIM studies, Dr. Greg Fehy has been able to demonstrate {a} using several epigenetic clocks we can accurately quantify an iindividual's biological age, (b) that everyone biologically ages at different rates due to genetics and other factors, and (c) that biological aging can be slowed or even reversed with the use of powerful FDA approved drugs. (see T.R.I.M.M. study, 2017 Standford University Medical Center).

Reversal of age was not the goal of the TRIIM study, it was a surprising clinical outcome not a single scientist expected. Instead, regenerating the thymus was the goal of the study. Explained more on this site, the thymus is responsible for training new 'T' cells how to protect us from cancer, pathogens, bacteria, and other threats.

By the age of 60, the thymus is nearly useless due to a condition called thymic involution. Without new 'T' cells, our chance of death increases with every passing year. This is why itts s critical that everyone eventually be treated to get the thymus generating the protection necessary to achieve a much longer life. Clinical trials have shown that once the thymus is regenerated, the adaptive immune system is restored to a much younger state and able to properly train the 'T' cells once again. But the benefit does not end there.

Regenerating the thymus involves the use of FDA approved drugs which forces the body top grow the thymus back. Clinical data indicate that the effects of the powerful drugs extend to regeneration of other organs and improved metrics reflecting a younger biological outcome. Indeed this younger biological state has been confirmed with the Horvath Epigenetic Clock by reading the methylation tags on an individuals DNA. Currently this treatment is prohibited, due to the FDA regulations but it is anticipated this treatment will become a major part of extending human lifespan. We will keep you posted.

mTor GENE, RAPAMYCIN, AND AUTOPHAGY

Rapamycin taken with other drugs has been shown to be safe and effective to ward off age related disease. and improve several healthspan metrics over and over again .Iin clinical studies across the globe. Rapamycin is a drug that targets a gene called mTor, down regulating the gene,. This down regulation is precisely what occurrs biologically when a human is in accute starvation. This, in turn, signals a cellular responds called autophagy.

Autophagy is a catabolic cellular reparation process whereas cells begin using damaged parts of cells for energy while regenerating the damaged parts. The result is measurable cellular revitalization causing improvements in several healtspan metrics. Clinical observations reported include, but are not limited to: overall improvements in physical and mental health, mprovements in several health metrics, improvements in immune response, improvements in joint health, increased mental health and clarity,, marked sexual libido, and even physical appearance.

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TAKING ADVANTAGE OF SCIENTIFIC BREATHROUGHS

Another area evolving quickly in medical science will without doubt change the way we approach individual health care. The days of waiting until you are sick to call a doctor are becoming obsolete.

Technology allowing an individual to monitor aspects of health and well being is a reality. These devices monitor in real time metrics such as blood pressure, blood sugar, oxygen saturation, etc.. These can also help us understanding the metabolic mode our body is in at any given time, which is critical to understanding the physical limitations. Certainly we would not want to be a catabolic mode if we are preparing to run a marathon. Conversely, we would not want to be in anabolic mode if we are trying to slim down.

Knowing our own state of health, and controlling the metabolic mode our bodies are in can be accomplished by actions which monitoring our biology with wearables is one of the most effective tools we now have to keeping you aware of health concerns. Real time monitoring though the use of wearables is critical to effective monitoring of health. This fact is particularly critical when an individual is seeking to slow, or even reverse the biological aging process. Several companies market reliable wearables that can deliver real time monitoring of blood sugar, blood pressure, stress levels, sleep patterns, exorcize rates and other importaint health related concerns.

A.I.M. we seek to not only introduce the patient to this technology, but to encourage utilization of these devices in its treatment plans. Real-time momitoring the state of health will be necessary for treatment involving the powerful drugs utilized. Having this information will not only aid in the level of safety, but will provide critical insight into the patients overall health, particularly when treating aging as a disease.

THE DISCOVERY THAT AGING CAN BE REVERSED

All the advances in preventitive medicine have catapolted us into a world where science, in many instances, can stop disease before it takes hold. Genetics indicate what we are prone to giving each of us the ability to know what we are in for, and be diligent when the time comes. to treat it. Aging itself brings on a host of problems most of us can count on being subjected to. We hope to change this, or at the least, significantly delay the onset of these problems.

For well over a hundred years medical science has came up with treatments such as bleeding the sick, and were credited by the masses. All these dangerous treatments looked like good science while a few other scientist kept their eye on aging, risking being labled a quack for it. Its looking more and more plausible that aging is the problem behind many disease and disorders.

The discovery that biological age reversal is possible was actually an accident. In 2019, Dr. Greg Fehy and Standford University ran the TRIMM study and later found its participants had experienced age reversal. using the DNA methylation markers to determine this. The scientific community was stunned. Since then, aging has been targeted, and a growing number of scientist are believing that aging is the underlying casue for most, if not all, disease. At A.I.M. we believe that belief is correct, and we treat our patients accordingly.

TAKING CONTROL OF YOUR OWN HEALTH

The best way to begin taking control of your own health is bringing your self up to speed with science. Do not assume your doctor knows everything because they do not. At A.I.M. we try to stay up to date within the field of longevity and stay on the cutting edge of the scientific discovery.

Scientific and medical journals, particularly PubMed, American's foremost medical resource journal, typically publishes study abstracts. These abstracts give the reader a close-to-laymens explanation of the study reusults. PubMed also serves as the primary source of knowledge for physicians who encounter questions as to cutting edge treatments or current clinical trial enrollments We suggest you take the time out to explore for yourself. Our blog will soon give way to daily posts regarding advances in the field of longevity science.

As a caution: credit YouTube videos with a cautious eye. Cross referencing claims on YouTube with the journals can be effective in weeding out bad science form good information. We will have some A.I.M. approved videos, but keep in mind most evidence is anecdotal. you find on non-accredited sites. When iit comes to aging related data, there is very little FDA approved, double blind, placebo clinical trial data as most of the scientific findings are relatively recent..

Click on the Treatment button in our menu to get an idea of a couple advocated treatments generally good for the majority of the population.

The treatments advocated by A.I.M. seek to treat what we believe is the undelying casue of disease, that is aging. Our treatments involves the use of mu powerful FDA approved drugs. We want the patient to fully understand the treatments as to allow the patient to monitor him/herself with technology accessible to the general public.

FINALLY

On a final note, A.I.M. seeks to make this affordable for the average person. While many millionaires able to afford extensive testing, they are still using the same drugs that achieved the break throughs in medicine.

What are these breakthroughs in medicine?

Relatively recent breakthroughs in medicine that show significant promise in effectively treating some of the diseases we now understand are age-related. Unfortunately these treatments and the technology is out of the reach of most Americans due to the FDA's diligent protection of the overall health of the American people. Doctors have a inherant reluctance to engage treatments that have not been FDA approved. It take extensive research and consultation to determine what treatments are safe and what's not yet ready for the masses.

There are a few FDA approved drugs that have been proven to be effective in human clinical trials and currently moving towards FDA approval for treating certain age related disease, however, due to 'aging ' not being an enumerated diagnosis by the Americans MedicalAssociation, any clinical trial designed to reverse aging still remains in the distant future.

Accordingly, through research and consulting treatments which are effective and safe can be identified. At A.I.M. we look to educate the patient with what's safe and allow the patient to make the determination if the risks outweigh the benefits. In some cases treatments have been shown to have little risk and startling benefits. In fact, the treatments A.I.M. advocate are used on many scientist and physicians themselves and these professionals are not afraid to admit it publicly.